A review of the smallpox vaccine adverse events active surveillance system
- PMID: 18284361
- DOI: 10.1086/524742
A review of the smallpox vaccine adverse events active surveillance system
Abstract
In response to concern about smallpox possibly being used as a biological weapon, the President of the United States launched the National Smallpox Pre-Event Vaccination Program on 13 December 2002. Given safety concerns, identifying potentially serious adverse events (SAEs) was an essential tool of the program. To monitor for SAEs, both enhanced passive surveillance and active surveillance systems were used. The enhanced passive system was built, in part, on the existing Vaccine Adverse Event Reporting System; the active system was implemented 24 January 2003. During January 2003-May 2005, the active system detected only 1 SAE in addition to those reported through the enhanced passive system. Furthermore, the active system was not universally used by states. With the enhancements to passive surveillance, the performance of enhanced passive surveillance was comparable to that of active surveillance. However, an active surveillance system may be important when there is no enhanced passive surveillance system available.
Similar articles
-
Neurologic adverse events associated with smallpox vaccination in the United States--response and comment on reporting of headaches as adverse events after smallpox vaccination among military and civilian personnel.BMC Med. 2006 Nov 10;4:27. doi: 10.1186/1741-7015-4-27. BMC Med. 2006. PMID: 17096855 Free PMC article.
-
Monitoring the safety of a smallpox vaccination program in the United States: report of the joint Smallpox Vaccine Safety Working Group of the advisory committee on immunization practices and the Armed Forces Epidemiological Board.Clin Infect Dis. 2008 Mar 15;46 Suppl 3:S258-70. doi: 10.1086/524749. Clin Infect Dis. 2008. PMID: 18284367
-
Smallpox vaccine adverse events among civilians--United States, January 24-February 18, 2003.MMWR Morb Mortal Wkly Rep. 2003 Feb 21;52(7):136. MMWR Morb Mortal Wkly Rep. 2003. PMID: 12617539
-
The US smallpox vaccination program: a review of a large modern era smallpox vaccination implementation program.Vaccine. 2005 Mar 18;23(17-18):2078-81. doi: 10.1016/j.vaccine.2005.01.012. Vaccine. 2005. PMID: 15755574 Review.
-
Smallpox vaccine: contraindications, administration, and adverse reactions.Am Fam Physician. 2003 Sep 1;68(5):889-96. Am Fam Physician. 2003. PMID: 13678138 Review.
Cited by 3 articles
-
Repeated high-dose (5 × 10(8) TCID50) toxicity study of a third generation smallpox vaccine (IMVAMUNE) in New Zealand white rabbits.Hum Vaccin Immunother. 2016 Jul 2;12(7):1795-801. doi: 10.1080/21645515.2015.1134070. Hum Vaccin Immunother. 2016. PMID: 26836234 Free PMC article.
-
Application of radiation technology in vaccines development.Clin Exp Vaccine Res. 2015 Jul;4(2):145-58. doi: 10.7774/cevr.2015.4.2.145. Epub 2015 Jul 29. Clin Exp Vaccine Res. 2015. PMID: 26273573 Free PMC article. Review.
-
Inhalational monkeypox virus infection in cynomolgus macaques.Front Cell Infect Microbiol. 2012 Sep 17;2:117. doi: 10.3389/fcimb.2012.00117. eCollection 2012. Front Cell Infect Microbiol. 2012. PMID: 23061051 Free PMC article.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Medical