Proponents say Crispr technology could transform agriculture and help feed a growing global population. Organic farmers and natural-food companies say it may pose health and environmental risks. 252

Before stepping down, Martin Sorrell faced a choice: endure an investigation into an allegation of personal misconduct, or leave the advertising giant he founded, say people familiar with the board and Mr. Sorrell.

Billions of dollars of goods sold each year by independent merchants on Amazon and other online marketplaces would be vulnerable to state sales taxes for the first time if justices reverse a quarter-century-old precedent. 245

As the U.S. weighs trying to rejoin the Trans-Pacific Partnership, any negotiations would likely be marked by years of back-and-forth as both the U.S. and countries still in the trade pact seek concessions. 101