When we think about scientific innovation, we tend to imagine the future: new drugs, ground-breaking methods, technologies that push the boundaries of what is possible. But good researchers don’t just look forward; they also reach into the past for inspiration—sometimes centuries into the past. That’s exactly what Dr. Miguel Prudêncio and his colleagues at Lisbon’s Instituto de Medicina Molecular are doing to create a approach to malaria vaccine development: they’re taking their cue from the very first vaccine.

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PMI excels at delivering our best tools quickly and efficiently to the people at greatest risk.

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After seven years and 14 rounds of Grand Challenges Explorations (GCE), you might think we’re finding the world to be out of big, bold ideas. But the challenge of “One great idea, $100,000 to prove it” continues to strike a chord with innovators around the world. This round, we received over 1,800 applications from 109 countries presenting creative solutions to the six challenges we posed. We are pleased to announce 52 awards to researchers in 19 countries.

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Halima Ndala uses an app on her smartphone to spread the word about malaria prevention in Mozambique.

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