Cancer Epidemiology

Non-malignant CNS tumors are not systematically registered in Europe.

The proportion of non-malignant cases was 49.8%, similar to malignant tumors.

Survival is still dramatically associated to both age and histological subtype.

First study assessing incidence and survival of CNS non-malignant tumors in Spain.

In 2013 a large case-control study linked long-term calcium channel blocker (CCB) use with breast cancer.

Since then, research groups have conducted studies to confirm/refute this association.

Our systematic review and meta-analysis critically reviewed relevant studies to 2016.

While an association seems unlikely, there remains uncertainty for use beyond 10 years.

We recommend further investigation of long-term use to provide further reassurance.

Cases who report working shifts are more likely to think shift work increases risk.

Belief about shift work does not affect controls’ reported shift work exposure.

Recalling shift work does not modify women’s beliefs about its effect on risk.

Recall bias does not appear to affect self-reported shift work exposure.

The combination of disease and exposure may modify beliefs about shift work.

The sensitivity was 72.0% and the positive predictive value was 81.9% for self-reported cancer history.

The highest sensitivity was observed for breast cancer and the lowest for liver cancer.

The validity of self-reported cancer history varied by sociodemographic factors.

20 year follow-up of brain cancer mortality risk in Gulf War veterans: 1991–2011.

Compared risk in potentially chemical weapons exposed and unexposed veterans.

No overall increased brain cancer mortality risk among exposed versus non-exposed.

Elevated brain cancer mortality risk immediately following the Gulf War among exposed.

Our high-risk screening clinic relies on patients to report family cancer history.

Most patients seeking familial CRC screening are too young for population screening.

Male gender and increasing age are associated with higher neoplastic yield.

Adenomas at index colonoscopy are predictive of adenomas at subsequent colonoscopy.

Our results support less intensive screening in patients <50yrs, and where index colonoscopy is normal.

Analysis of cancer incidence data to assess sex disparity in a Chinese population.

The incidences of most malignant cancers were higher in males than in females.

Age-specific male predominance occurred in the ten commonest cancers for most ages.

The study evaluated whether telomere length is causally associated with HCC risk in Chinese population with Mendelian randomization approach.

Our results indicated that a genetic background that favors longer or shorter telomere length may increase HBV-related HCC risk—a U-shaped association.

Subgroup analysis did not reveal significant heterogeneity between different age, gender, smoking status and drinking status groups.

Mortality rates for prostate cancer increased in Brazil in the last 30 years.

Increase in prostate cancer mortality rates was due to Brazilian population aging.

Cohort effects showed risk of death was higher for younger generations in Brazil.

There is inequality in access to oncology services between Brazilian regions.

We have determined if socio-economic and other factors may play a role in survival from renal tumours in children and young people.

The study did not detect a significant social gradient in renal tumour survival.

Tumour stage was a strong predictor of survival irrespective of age.

Interventions should focus on early diagnosis and treatment.

Prevalence proportion of tracheal invasion is rare in thyroid cancer.

Peak age of incidence was higher in tracheal invasion than overall thyroid cancer.

Some patients had long-term tracheostomy placement despite tracheal reconstruction.

Compared to the Western countries, the scientific evidences of effectiveness of HPV-based cervical cancer screening is limited in Japan.

We initiated a randomized trial entitled CervIcal cancer screening Trial by Randomization of HPV testing intervention for Upcoming Screening (CITRUS).

Insights from CITRUS will provide future prospects for cervical cancer screening focused on the use of HPV testing.

Prostate and breast cancer screening independent at the regional level.

PSA screening associated with regional intensity of healthcare.

These screening practices should be understood differently for policy implications.

Further work needed to understand factors behind regional variations in screening.

Among the first prospective studies of neighborhood data and colorectal cancer risk.

Used a comprehensive suite of attributes to characterize the obesogenic environment.

Analyzed data from the large racial/ethnically diverse Multiethnic Cohort.

Traffic density was modestly associated with colorectal cancer risk among males.

Penile cancer remains rare in France without change in incidence over time.

Survival stays low due to lack of early diagnosis and limited improvement in care.

Patients should be encouraged to search for medical advice to improve prognosis.

Clinical trials internationally conducted are also needed to improve care.

The most common site of SPCs in gastric FPC patients was digestive organs.

The estimated 10-year cumulative incidence of metachronous SPC was 4.8%.

Compared to the general population, an increased risk of metachronous SPC was seen.

H. pylori antibody reactivity pattern is related to non-cardia gastric cancer risk.

Combined high seroreactivities for several H. pylori proteins could identify a decreased risk.

Cagδ seropositivity was independently associated with a lower risk.