22 April 2016
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| 11:00 PM | All In With Chris Hayes |
| 12:00 AM | The Rachel Maddow Show |
| 1:00 AM | Lockup - Grand Rapids: Extended Stay - Piece of Cake: A repeat offender comes to terms with his past; inmate is caught off guard and viciously assaulted. |
| 2:00 AM | Lockup - Grand Rapids: Extended Stay - Outcast: An inmate attempts to leave jail, the hard way; an outcast inmate's comment leads to violence. |
| 3:00 AM | Lockup - Tulsa: Extended Stay - Two Degrees of Murder: A pregnant woman is charged with her husband's murder; inmate pays the price for disobeying orders. |
| 4:00 AM | Lockup - Tulsa: Extended Stay - The Bad Good Friday: Murderous shooting spree erupts on a religious holiday; a new inmate catches the staff's attention. |
| 5:00 AM | Lockup: Raw - Hooch and Crafts |
| 5:30 AM | Your Business: A focus on issues facing small business in the United States. |
| 6:00 AM | The Rachel Maddow Show |
| 7:00 AM | The Place for Politics 2016 |
| 8:00 AM | The Place for Politics 2016 |
| 9:00 AM | The Place for Politics 2016 |
| 10:00 AM | The Place for Politics 2016 |
| 11:00 AM | The Place for Politics 2016 |
| 12:00 PM | The Place for Politics 2016 |
| 1:00 PM | The Place for Politics 2016 |
| 2:00 PM | The Place for Politics 2016 |
| 3:00 PM | Caught on Camera - Chaos in the Court : Courtroom deputies caught by surprise; victims' families lashing out, even judges pushed too far. |
| 4:00 PM | Caught on Camera - Viral Videos - Millions Served : Videos that millions have to see; original, funny, bizarre, must be passed on. |
| 5:00 PM | Caught on Camera - Politics Gone Wild : Politicians show they can take it as well as dish it out. |
| 6:00 PM | Caught on Camera - A Hard Day's Work : Embarrassing, funny, scary, and unbelievable scenarios on the job. |
| 7:00 PM | Caught on Camera - Narrow Escape : Inches away from disaster, only seconds away from death. |
| 8:00 PM | Caught on Camera - On Patrol : Hidden cameras see it all, the eyewitness that never lies. |
| 9:00 PM | Lockup - Grand Rapids: Extended Stay - Jailing: A gangbanger squares off with his victim's family and another inmate. |
| 10:00 PM | Lockup - Grand Rapids: Extended Stay - And Baby Makes Three?: An inmate tries creating a popular dish; a pair of lovers might have another mouth to feed. |
| 11:00 PM | Lockup - Grand Rapids: Extended Stay - The Gamble: An inmate with a big personality faces another problem; four inmates enter the system. |