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Saturday 16th April 2016
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Gene Find Could Help Understanding Of Strokes

Friday, 8th April 2016 01:40

A new gene linked to "small blood vessel" strokes has been found, and it is hoped the discovery may improve understanding of the condition.

Researchers have identified a gene called FOXF2, which increases the risk of having a stroke due to blocked small blood vessels in the brain.

Previous studies have found genes linked to strokes caused by reduced blood flow to the brain, and bleeding.

Lead scientist Professor Sudha Seshadri, from Boston University Medical Center, said: "Unravelling the mechanisms of small vessel disease is essential for the development of therapeutic and preventive strategies for this major cause of stroke."

The study highlights a novel biological pathway affecting pericytes, which is a kind of cell in the walls of small arteries and capillaries.

The scientists said small blood vessel disease in the brain is also a major factor in dementia risk and is associated with gait problems and depression.

The findings are published in the journal The Lancet Neurology.