Genomics Implementation

Fact Sheet: Implementing Evidence-based Genomic Tests and Family Health History [PDF 1.04 MB]

What public health can do now in human genomics to save lives and improve health

This page summarizes current information on genomic applications that are ready to be integrated into public health practice to save lives, improve health and quality of life. The focus at this time is on three Tier I applications: Hereditary Breast/Ovarian Cancer Syndrome, Lynch Syndrome and Familial Hypercholesterolemia, but information about other Tier I applications will be added in the near future. The page includes information about completed and ongoing projects spearheaded by state health departments and their partners, and recommendations from evidence based groups which can be applied  at the state or local level.  Please contact us at genetics@cdc.gov if you are aware of a statewide or other project not currently included which should be highlighted on this page.

Resources

• Classification of Genomic Applications by Levels of Evidence
• State Implementation Activities Clickable Map
• Public Health Genomic Tier 1 Tool Kit
• Healthy People 2020 Genomics Objectives 

Reports

• Priorities for Public Health Genomics: 2012-2017. [PDF 5.35 MB] University of Michigan Center for Community and Public Health Genomics 2012
• Report and Recommendations from the September 7, 2012 CDC Workshop: New Strategies in Public Health Genomics Actions to Save Lives Now [ PDF 951.81 KB]. University of Michigan Center for Community and Public Health Genomics. APHA Genomics Forum
  
• CDC paper: Public health action in genomics is needed now beyond newborn screening. By S Bowen et al. Public Health Genomics 2012
• New strategies in public health in genomics beyond newborn screening: a working meeting 9/17/2012 and development of an action plan (CDC Blog)
• Current priorities for public health practice in addressing the role of human genomics in improving population health. Khoury MJ et al. Am J Prev Med 2011.

Videos and Podcasts

• A video resource: Genetics and BRCA in Primary Care (October 14,, 2014)
• A video resource: Public health genomics implementation to save lives - from national vision to state success (March 6, 2014)
• A video interview on Tier 1 genomic application and pioneer states (March 6, 2014)
• Using genomics to prevent cancer now (March 6, 2014)
• CDC Video: A Tiered Approach to Integrating Genomic Tests Into Your Practice (January 14, 2013)
• CDC Video: Cascade genetic screening and public health practice: an idea whose time has come (October 18, 2012)
• Hereditary Breast and Ovarian Cancer: BRCA and Your Patient (October 10,2011)
• Genetic Testing for Lynch Syndrome in Colorectal Cancer (February 7, 2011)
• Cascade screening for Familial Hypercholesterolemia (September 20, 2010)

Forthcoming Resources

• Surveillance Indicators