A database of Neisseria genomes created by the Jordan Lab in the School of Biology, GIT, funded by Centers for Disease Control and Prevention to advance research into the genetic causes of virulence in N. meningitidis
A database of Neisseria genomes created by the Jordan Lab in the School of Biology, GIT, funded by Centers for Disease Control and Prevention to advance research into the genetic causes of virulence in N. meningitidis
Neisseria meningitidis is a gram-negative encapsulated bacterium that is the leading cause of bacterial meningitis worldwide. Meningococcal meningitis and sepsis can cause death within hours and are particularly lethal in young children and adolescents. Each year, there are two to three thousand cases of meningococcal meningitis in the United States with about a 10% case fatality rate. In sub-Saharan Africa, there are approximately 70,000 cases each year with similar or higher fatality rates.
The Jordan Lab coordinates with the Meningitis Laboratory at the Centers for Disease Control and Prevention (CDC) to characterize the genomes of an increasing number of virulent and nonvirulent N. meningitidis strains as they become available. Our lab is charged with developing a platform for storing, disseminating and analyzing these genomes.