Fungal Diseases

Treatment for Aspergillosis

Allergic forms of aspergillosis

For allergic forms of aspergillosis such as allergic bronchopulmonary aspergillosis (ABPA) or allergic Aspergillus sinusitis, the recommended treatment is itraconazole, a prescription antifungal medication. Corticosteroids may also be helpful.

Invasive aspergillosis

Invasive aspergillosis needs to be treated with prescription antifungal medication, usually voriconazole. There are other medications that can be used to treat invasive aspergillosis in patients who can’t take voriconazole or whose infections don’t get better after taking voriconazole. These include itraconazole, lipid amphotericin formulations, caspofungin, micafungin, and posaconazole. Whenever possible, immunosuppressive medications should be discontinued or decreased. People who have severe cases of aspergillosis may need surgery.

Healthcare providers can click here to see the Infectious Disease Society of America’s Treatment of Aspergillosis Clinical Practice Guidelines [PDF - 34 pages].