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HomoloGene is a system for automated detection of homologs among the annotated genes of several completely sequenced eukaryotic genomes.

HomoloGene Release 67 Statistics



Initial numbers of genes from complete genomes, numbers of genes placed in a homology group, and the numbers of groups for each species.

Species   Number of Genes   HomoloGene
  Input Grouped   groups
M.oryzae 12,832  7,330   6,403
M.mulatta 22,566  17,151   16,706
H.sapiens 19,217  18,867   18,473
P.troglodytes 19,655  17,367   17,078
C.lupus 19,176  17,800   17,186
B.taurus 21,121  18,771   17,458
M.musculus 21,432* 20,744   18,858
R.norvegicus 21,943  19,868   17,882
G.gallus 16,731  14,171   13,149
D.rerio 26,326  20,504   14,183
D.melanogaster 13,555  9,252   7,713
A.gambiae 12,460  8,827   7,500
C.elegans 20,185  8,698   4,811
S.pombe 5,018  3,238   2,946
S.cerevisiae 5,882  4,854   4,373
K.lactis 4,978  4,404   4,338
E.gossypii 4,722  3,932   3,888
N.crassa 9,821  6,301   6,158
A.thaliana 27,388  19,965   11,078
O.sativa 28,456  17,086   10,431


'*' indicates organisms where new genome annotation data is used in this build.


Last updated on: Thu Dec 13 2012



We have recently adopted a new build procedure that makes use of amino acid sequence searching (blastp) to find more distant relationships, but the procedure still refers to the DNA sequence for computation of some of the statistics. The matching strategy is guided by the taxonomic tree such that more closely related organisms are compared first. Moreover, HomoloGene entries now include paralogs in addition to orthologs.




 

What's New
HomoloGene 67 includes genes from the the latest mouse genome release (GRCm38).


Related Resources
Protein Clusters

List of Genomes

Taxonomy