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December 31, 2011
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Anabolic Steroid Abuse

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Doctor to Patient

Steroid Abuse

Medical Author: Melissa Conrad Stöppler, MD
Medical Editor: William C. Shiel Jr., MD, FACP, FACR and Jay W. Marks, MD

Learn about the physical and emotional side effects of steroid abuse. Steroids are a class of compounds that share a similar chemical structure. This broad group of chemicals includes many normal substances in the body (such as cholesterol), vitamins (vitamin D), hormones (for example, the sex hormones and their derivatives), and drugs given to treat inflammation (hydrocortisone, prednisone). The adrenal glands secrete a number of steroid hormones, known as corticosteroids, that are important for the maintenance of blood pressure, blood glucose levels, salt and water balance, and other critical body processes. However, when we speak of steroid abuse by athletes, doctors are referring to the misuse of the so-called "anabolic steroids," which are manufactured drugs similar to the male sex hormone testosterone.

The term anabolic refers to the muscle-building properties of these man-made substances. Available legally only by prescription, anabolic steroids are sometimes prescribed by doctors to treat conditions in which testosterone levels are abnormally low, or in certain chronic conditions such as AIDS that are associated with loss of muscle mass.


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athletes, drug abuse, side effects, treatment, symptoms, teens, consequences
Doctor to Patient

What are anabolic steroids?

Performance-enhancing drugs are no longer just for bodybuilders or pro athletes who are willing to try illegal and potentially dangerous means to improve their body's function. These drugs are being used every day by people of all ages, from middle-school, high-school, and college students to older recreational athletes.

Anabolic steroids are one type of performance-enhancing drug. They mimic testosterone in the body to enhance performance by making muscle cells larger and by allowing the body to recover more quickly from the stress of exercise. Slang for anabolic steroids is "roids."

There are two types of steroids that are naturally produced in the body:

Catabolic steroids or glucocorticoids are part of the body's response to stress. The word catabolic comes from the Greek word meaning to "throw down," and these steroids help break down large chemicals into smaller ones. For example, cortisol helps glycogen, a large molecule that is stored in the liver, metabolize into glucose, a small molecule that can be used for energy by the body. Cortisol is manufactured in the adrenal glands and is required for many of the basic functions of the body, including glucose metabolism, the immune response to infection, and protein, fat, and carbohydrate metabolism. Prednisone, hydrocortisone, and dexamethasone are examples of steroids that are used to treat a range of illnesses from asthma and COPD to rheumatoid arthritis and allergic reactions.

Anabolic androgenic steroids are steroids that mimic testosterone in the body. Anabolic refers to the properties of these drugs to increase production of proteins that act as building blocks for muscle cells, bone, and other tissues within the body. The androgenic response (andro=male + genic=formation) describes the increased male features (secondary sexual characteristics) that occur as a result of androgenic steroids, including facial, body, and pubic hair, deepened voice, and increased sex drive or libido. The few medical indications for prescribing these medications are due to a lack of testosterone production in the body, either because of inborn errors of metabolism or because of illnesses that decrease production. Some physicians believe that decreased testosterone that occurs normally with aging is an indication for replacement therapy with anabolic steroids, but their use in otherwise healthy older patients is still controversial because of the potential serious side effects.

There are many anabolic steroids that have been manufactured over the past decades. The goal of the manufacturing chemists is to promote the anabolic effect of the drug while decreasing the androgenic effects that are most often associated with potential side effects that can be life-threatening. Examples of anabolic steroids include the following:




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Puberty facts

  • Puberty is the time of sexual maturation and achievement of fertility.
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  • Body fat and/or body composition may play a role in regulating the onset of puberty.
  • Puberty is associated with development of secondary sex characteristics and rapid growth.
  • Some medical conditions may worsen or first become apparent at puberty.
  • Precocious puberty is puberty that occurs earlier than usual. It is more common in girls than in boys.

What is puberty?

Puberty is the time at which growing boys or girls begin the process of sexual maturation. Puberty involves a series of physical stages or steps that lead to the achievement of fertility and the development of the so-called secondary sex chara...

Read the Puberty article »





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