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Once-Daily Treatment Can Help

Do you treat your chronic osteoarthritis pain with medication each time you feel it get worse? Maybe it's time to rethink your approach. Cymbalta can help.

Find Out How

Have a Better Conversation With Your Doctor

Doctor's appointments can be short and rushed. It can be hard to remember important details like how long you've been experiencing chronic OA pain and what seems to trigger it. Make the most of your time. Be prepared.

Start Now

Knowing What to Expect From Cymbalta

The chronic OA pain you have now didn't happen overnight. Feeling better may take time. Cymbalta can help manage your chronic osteoarthritis pain over time. Learn what to expect if you're new to Cymbalta.

Find Out How

How do you Manage Your Chronic OA Pain?

Do you treat your chronic osteoarthritis pain only when it worsens? That’s not your only option. Find out how once-daily, Cymbalta can help manage chronic OA pain.

Have a Better Conversation with Your Doctor

You need to tell your doctor how you feel, but appointments are short and rushed. Learn how to make the most of your time together.

Get Help Starting Treatment

Sometimes it’s difficult to start a new treatment. But here’s something that can help. If you and your doctor are not satisfied with your treatment with Cymbalta, you may be reimbursed up to 100% of your out-of-pocket costs for the first 60 days.*

* Restrictions apply. See the full Terms and Conditions.
This offer is not a guarantee of efficacy. It provides a trial period that may help patients and doctors to assess the efficacy, safety, and tolerability of Cymbalta.

Next Article:

Important Safety Information About Cymbalta

The most important information you should know about Cymbalta:

Antidepressants can increase suicidal thoughts and behaviors in children, teens, and young adults. Suicide is a known risk of depression and some other psychiatric disorders. Call your doctor right away if you have new or worsening depression symptoms, unusual changes in behavior, or thoughts of suicide. Be especially observant within the first few months of treatment or after a change in dose. Approved only for adults 18 and over.

Cymbalta® (duloxetine HCl) is not for everyone. Do not take Cymbalta if you:

  • have recently taken a type of antidepressant called a monoamine oxidase inhibitor (MAOI) or Mellaril® (thioridazine)
  • have uncontrolled narrow-angle glaucoma (increased eye pressure)

Talk with your healthcare provider:

  • about all your medical conditions, including kidney or liver problems, glaucoma, diabetes, seizures, or if you have bipolar disorder. Cymbalta may worsen a type of glaucoma or diabetes
  • if you have itching, right upper belly pain, dark urine, yellow skin/eyes, or unexplained flu-like symptoms while taking Cymbalta, which may be signs of liver problems. Severe liver problems, sometimes fatal, have been reported
  • about your alcohol use
  • about all your medicines, including those for migraine, to address a potentially life-threatening condition. Symptoms may include high fever, confusion, and stiff muscles
  • if you are taking NSAID pain relievers, aspirin, or blood thinners. Use with Cymbalta may increase bleeding risk
  • if you have skin blisters, serious or peeling rash, hives, or mouth sores while taking Cymbalta. These may be serious, possibly life-threatening, skin reactions
  • before stopping Cymbalta or changing your dose
  • if you experience dizziness or fainting upon standing while taking Cymbalta. This tends to occur in the first week or when increasing the dose, but may occur at any time during treatment
  • about your blood pressure. Cymbalta can increase your blood pressure. Your healthcare provider should check your blood pressure prior to and while taking Cymbalta
  • if you experience headache, weakness, confusion, problems concentrating, memory problems, or feel unsteady while taking Cymbalta, which may be signs of low sodium levels
  • if you develop problems with urine flow while taking Cymbalta
  • if you are pregnant or plan to become pregnant during therapy, or are breast-feeding

Most common side effects of Cymbalta (this is not a complete list):

  • nausea, dry mouth, sleepiness, fatigue, constipation, dizziness, decreased appetite, and increased sweating

You are encouraged to report negative side effects of Prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.

Other safety information about Cymbalta:

  • Cymbalta may cause sleepiness and dizziness. Until you know how Cymbalta affects you, you should not drive a car or operate hazardous machinery.
  • People age 65 and older who took Cymbalta reported more falls, some resulting in serious injuries.

How to take Cymbalta:

Take Cymbalta exactly as directed by your healthcare provider. Cymbalta should be taken by mouth. Do not open, break or chew capsule; it must be swallowed whole. Cymbalta can be taken with or without food.

Cymbalta is available by prescription only.

See Prescribing Information, including Boxed Warning about antidepressants and risk of suicide, and Medication Guide.

DD CON ISI 12SEP2011

Eli Lilly and Company
Lilly Corporate Center
Indianapolis, IN - USA

DD73948 ©Lilly USA, LLC. 2011 ALL RIGHTS RESERVED.
Cymbalta is a registered trademark of Eli Lilly and Company.
This site is intended for US residents age 18 and over. All rights reserved.

WebMD does not endorse any specific product, service, or treatment.

Cymbalta is indicated for the management of chronic musculoskeletal pain due to chronic osteoarthritis pain.

Important Safety Information About Cymbalta

The most important information you should know about Cymbalta:

Antidepressants can increase suicidal thoughts and behaviors in children, teens, and young adults. Suicide is a known risk of depression and some other psychiatric disorders. Call your doctor right away if you have new or worsening depression symptoms, unusual changes in behavior, or thoughts of suicide. Be especially observant within the first few months of treatment or after a change in dose. Approved only for adults 18 and over.

Cymbalta® (duloxetine HCl) is not for everyone. Do not take Cymbalta if you:

  • have recently taken a type of antidepressant called a monoamine oxidase inhibitor (MAOI) or Mellaril® (thioridazine)
  • have uncontrolled narrow-angle glaucoma (increased eye pressure)

Talk with your healthcare provider:

  • about all your medical conditions, including kidney or liver problems, glaucoma, diabetes, seizures, or if you have bipolar disorder. Cymbalta may worsen a type of glaucoma or diabetes
  • if you have itching, right upper belly pain, dark urine, yellow skin/eyes, or unexplained flu-like symptoms while taking Cymbalta, which may be signs of liver problems. Severe liver problems, sometimes fatal, have been reported
  • about your alcohol use
  • about all your medicines, including those for migraine, to address a potentially life-threatening condition. Symptoms may include high fever, confusion, and stiff muscles
  • if you are taking NSAID pain relievers, aspirin, or blood thinners. Use with Cymbalta may increase bleeding risk
  • if you have skin blisters, serious or peeling rash, hives, or mouth sores while taking Cymbalta. These may be serious, possibly life-threatening, skin reactions
  • before stopping Cymbalta or changing your dose
  • if you experience dizziness or fainting upon standing while taking Cymbalta. This tends to occur in the first week or when increasing the dose, but may occur at any time during treatment
  • about your blood pressure. Cymbalta can increase your blood pressure. Your healthcare provider should check your blood pressure prior to and while taking Cymbalta
  • if you experience headache, weakness, confusion, problems concentrating, memory problems, or feel unsteady while taking Cymbalta, which may be signs of low sodium levels
  • if you develop problems with urine flow while taking Cymbalta
  • if you are pregnant or plan to become pregnant during therapy, or are breast-feeding

Most common side effects of Cymbalta (this is not a complete list):

  • nausea, dry mouth, sleepiness, fatigue, constipation, dizziness, decreased appetite, and increased sweating

You are encouraged to report negative side effects of Prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.

Other safety information about Cymbalta:

  • Cymbalta may cause sleepiness and dizziness. Until you know how Cymbalta affects you, you should not drive a car or operate hazardous machinery.
  • People age 65 and older who took Cymbalta reported more falls, some resulting in serious injuries.

How to take Cymbalta:

Take Cymbalta exactly as directed by your healthcare provider. Cymbalta should be taken by mouth. Do not open, break or chew capsule; it must be swallowed whole. Cymbalta can be taken with or without food.

Cymbalta is available by prescription only.

See Prescribing Information, including Boxed Warning about antidepressants and risk of suicide, and Medication Guide.

DD CON ISI 12SEP2011

Important Safety Information and Boxed Warning
Prescribing Information | Medication Guide

Free 30-Capsule Trial

Get Started with a Free 30-Capsule Trial of Cymbalta

Click here for details.

Learning more about chronic osteoarthritis pain can help you better understand your treatment options and the importance of sticking with a treatment plan.