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Zinc for Colds: Lozenges & Nasal Sprays

Zinc for Colds: Lozenges & Nasal Sprays

Introduction

You've probably heard a lot about zinc for colds. But is zinc really effective for reducing the duration of cold symptoms? Here's what you should know about zinc and colds.

What is zinc?

Zinc is an essential mineral that is found in almost every cell. Zinc has antioxidant effects and is vital to the body's resistance to infection. It's also important for tissue repair.

Zinc is found naturally in shellfish, beef and other red meats, nuts and seeds, beans, and milk and cheese. Tea, coffee, and certain medications may interfere with zinc absorption in the intestines.

Is zinc an effective cold remedy?

Researchers have studied the use of zinc as a cold remedy and as a way to treat the cold virus. Still, the data from years of scientific studies is mixed.

In some studies, researchers found that zinc lozenges or nasal sprays decreased the duration of colds. In other studies, they found no differences in cold symptoms between those who took zinc and those who took a placebo or sugar pill.

What do these findings on zinc and colds mean to you and your family? For now, the study results on using zinc as a cold remedy are inconclusive. For every study showing a positive benefit with zinc, there's another study showing no benefit at all. In fact, it's believed that if there is any benefit in taking zinc or zinc lozenges, it is very minor.

Is zinc a safe cold remedy?

The effectiveness of zinc as a cold remedy relies on frequent dosing during the illness, which means zinc lozenges must be taken every two to four hours. Short-term use of zinc — less than 5 days — has not lead to serious side effects but can cause mouth irritation and stomach upset. However, experts recommend that zinc should not be taken for more than 5 days. Long-term use of zinc — for more than 6 weeks — can lead to copper deficiency.

Zinc nasal sprays are known to cause a loss of the sense of smell in animals, and there have been several reports of people losing their sense of smell from zinc nasal sprays. Due to this risk of a loss of smell, many experts recommend that you avoid zinc nasal sprays completely.

Zinc supplements are not recommended for children as they are even more sensitive to zinc and develop side effects at much lower zinc levels.

Yes, zinc is necessary for optimal health and is safe to take when ingested through food sources such as seafood and eggs. But supplementing with higher doses of zinc, particularly long term, can be toxic.

What's the bottom line on zinc and colds?

While some research has shown some benefit from zinc lozenges and nasal sprays, studies have been inconsistent and additional research is needed to see if, in fact, zinc is an effective cold remedy. Zinc's side effects may outweigh any potential benefit and the benefit may be minimal at best.

WebMD Medical Reference

Sources: NIH Office of Dietary Supplements: "Zinc." American Family Physicians: "Treatment of the Common Cold." Scientific American: "No proof zinc lozenges help cold symptoms." US Pharmacist: "Zinc and the Common Cold: What Pharmacists Need to Know." Medscape: "Efficacy of Zinc Lozenges Against Common Cold Viruses." Oregon State University, Micronutrient Information Center: "Zinc."

Reviewed by Michael W. Smith, MD on December 18, 2007

© 2007 WebMD, Inc. All rights reserved.

Reference: FDA Prescribing Information


Last Editorial Review: 2/28/2008




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Suggested Reading on Zinc for Colds: Lozenges & Nasal Sprays by Our Doctors

  • Related Diseases & Conditions

    • Upper Respiratory Infection
      • An upper respiratory infection is a contagious infection of the structures of the upper respiratory tract, which includes the sinuses, nasal passages, pharynx, and larynx. Common causes of an upper respiratory infection include bacteria and viruses such as rhinoviruses, group A streptococci, influenza, respiratory syncytial, whooping cough, diphtheria, and Epstein-Barre. Examples of symptoms of upper respiratory infection include sneezing, sore throat, cough, fever, and nasal congestion. Treatment of upper respiratory infection are generally with OTC medication and home remedies.
    • Common Cold
      • The common cold (viral upper respiratory tract infection) is a contagious illness that may be caused by various viruses. Symptoms include a stuffy nose, headache, cough, sore throat, and maybe a fever. Antibiotics have no effect upon the common cold, and there is no evidence that zinc and vitamin C are effective treatments.
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      • Influenza (flu) is a respiratory illness caused by a virus. Flu symptoms include fever, cough, sore throat, runny nose, headache, fatigue, and muscle aches. The flu may be prevented with an annual influenza vaccination.
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      • Before treating a cold, the flu, or allergies with over-the-counter (OTC) medications, it's important to know what's causing the symptoms, which symptoms one wishes to relieve, and the active ingredients in the OTC product. Taking products that only contain the medications needed for relieving your symptoms prevents ingestion of unnecessary medications and reduces the chances of side effects.
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Zinc for Colds: Lozenges & Nasal Sprays

What is influenza?

Influenza, commonly called "the flu," is an illness caused by RNA viruses that infect the respiratory tract of many animals, birds, and humans. In most people, the infection results in the person getting fever, cough, headache, and malaise (tired, no energy); some people also may develop a sore throat, nausea, vomiting, and diarrhea. The majority of individuals has symptoms for about one to two weeks and then recovers with no problems. However, compared with most other viral respiratory infections, such as the common cold, influenza (flu) infection can cause a more severe illness with a mortality rate (death rate) of about 0.1% of people who are infected with the virus.

The above is the usual situation for the yearly occurring "conventional" or "seasonal" flu strains. However, there are situations in which some flu outbreaks are severe. These severe outbreaks occur when the human population is exposed to a flu strain against which the populati...

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