Leishmaniasis (cont.)
Can leishmaniasis be prevented?
Leishmaniasis can be prevented by avoiding
the bite of the sand fly. Simple insect precautions, including protective
clothing (long sleeves, long pants, socks) and insect repellents containing N,N-diethylmetatoluamide (DEET), reduce the risk of bites. Because sand flies are
most active in the evening and nighttime, efforts should be made to reduce
exposure in sleeping accommodations. Sand flies are very small and are even
smaller than mosquitoes. Finely meshed bed nets may be used and may be
impregnated with insecticides such as
permethrin (Elimite, NIX) or deltamethrin. Sand flies are
weak fliers, so bed nets should be tucked under mattresses. Clothing may also be
treated with permethrin to repel insects. Domestic dogs can be fitted with an
insecticide-containing collar, such as the Scalibor collar, which contains
deltamethrin.
From a larger perspective, treatment of infected animals and people along
with judicious use of insecticide has the potential to reduce the burden of
infection in endemic areas. This approach is being tried in several regions with
mixed success. There is no vaccine that is currently approved for human use, but
research in this area is ongoing.
Where can people get more information about leishmaniasis?
REFERENCES:
Amato, V.S., F.F. Tuon, A.M. Siqueira, A.C. Nicodemo, and V.A. Neto. "Treatment of
Mucosal
Leishmaniasis in Latin America: Systematic Review." Am J Trop Med Hyg.
77 (2007): 266-274.
Daneshbod, Y., A. Oryan, M. Davarmanesh, S. Shirian, S. Negahban, A. Aledavood,
M.A. Davarpanah, H. Soleimanpoor, and K. Daneshbod. "Clinical, Histopathologic, and
Cytologic Diagnosis of Mucosal Leishmaniasis and Literature Review." Arch Pathol
Lab Med. 135 (2011): 478-482.
Desjeux, P. "Prevention of Leishmania donovani Infection." BMJ. 341 Dec.
29, 2010: c6751.
García, A.L., R. Parrado, E. Rojas, R. Delgado, J.C. Dujardin, and R. Reithinger.
"Leishmaniases in Bolivia: Comprehensive Review and Current Status." Am J Trop Med Hyg. 80 (2009): 704-711.
Scott, P. "Leishmania -- a Parasitized Parasite." N Engl J Med. 364 (2011): 1773-1774.
Last Editorial Review: 8/1/2011