Melissa Conrad Stöppler, MD, is a U.S. board-certified Anatomic Pathologist with subspecialty training in the fields of Experimental and Molecular Pathology. Dr. Stöppler's educational background includes a BA with Highest Distinction from the University of Virginia and an MD from the University of North Carolina. She completed residency training in Anatomic Pathology at Georgetown University followed by subspecialty fellowship training in molecular diagnostics and experimental pathology.
Dr. Shiel received a Bachelor of Science degree with honors from the University of Notre Dame. There he was involved in research in radiation biology and received the Huisking Scholarship. After graduating from St. Louis University School of Medicine, he completed his Internal Medicine residency and Rheumatology fellowship at the University of California, Irvine. He is board-certified in Internal Medicine and Rheumatology.
Interstitial lung disease is a term used to refer to a particular type of
inflammation of the interstitium of the lungs. The interstitium is the tissue
that surrounds and separates the tiny air sacs (alveolae) in the lungs.
Interstitial lung disease involves an inflammation of this supportive tissue
between the air sacs rather than inflammation in the air sacs themselves.
Interstitial inflammation is typically a diffuse process that occurs all over
the lungs and is not confined to one location.
Sometimes the term "interstitial pneumonia" is used for certain forms of
interstitial lung disease. Technically, however, the term "pneumonia" refers to
inflammation of the lung tissue that is usually associated with infection.
Because interstitial lung disease has a number of causes (most of which are not
related to infection), the term "interstitial pneumonitis" is occasionally used
to refer to the inflammation that occurs in the absence of true infection.
What causes interstitial lung disease?
Interstitial lung disease is felt to be caused by a misdirected immune or
healing reaction to a number of factors, including:
Sometimes, the process of inflammation and scarring of the interstitial
tissues of the lungs develops in the absence of a known cause. When no cause can
be identified, this is referred to as idiopathic (unknown cause) interstitial
lung disease or idiopathic pulmonary fibrosis. Depending upon the location,
severity, and pattern of lung involvement, the idiopathic interstitial lung
diseases have been further subdivided into categories. Examples of different
types of idiopathic interstitial lung disease include:
usual interstitial
pneumonitis (UIP),
bronchiolitis
obliterans with organizing pneumonia (BOOP),
Congestive heart failure (CHF) is a condition in which the heart's function as a pump is inadequate to meet the body's needs. A poor blood supply resulting from congestive heart failure may cause the body's organ systems to fail, leading to a weakened heart muscle and fluid accumulation in the lungs and body tissue. There are many diseases that can impair pumping efficiency and symptoms of congestive heart failure including fatigue, diminished exercise capacity, shortness of breath, and swelling. Treatments include lifestyle modifications, medications, heart transplant, and therapy.
Rheumatoid arthritis is an autoimmune disease that causes chronic inflammation of the joints, the tissue around the joints, as well as other organs in the body. Because it can affect multiple other organs of the body, rheumatoid arthritis is referred to as a systemic illness and is sometimes called rheumatoid disease.
Pneumonia is inflammation of one or both lungs with consolidation. Pneumonia is frequently but not always due to infection. The infection may be bacterial, viral, fungal or parasitic. Symptoms may include fever, chills, cough with sputum production, chest pain, and shortness of breath.
Sarcoidosis, a disease resulting from chronic inflammation, causes small lumps (granulomas) to develop in a great range of body tissues and can appear in almost any body organ. However, sarcoidosis most often starts in the lungs or lymph nodes.
Chronic cough is a cough that does not go away and is generally a symptom of another disorder such as asthma, allergic rhinitis, sinus infection, cigarette smoking, GERD, postnasal drip, bronchitis, pneumonia, medications, and less frequently tumors or other lung disease. Treatment of chronic cough is dependant upon the cause.
Scleroderma is an autoimmune disease of the connective tissue. It is characterized by the formation of scar tissue (fibrosis) in the skin and organs of the body, leading to thickness and firmness of involved areas. Scleroderma is also referred to as systemic sclerosis, and the cause is unknown. Treatment of scleroderma is directed toward the individual features that are most troubling to the patient.
Pulmonary fibrosis is scarring throughout the lungs. Pulmonary fibrosis can be caused by many conditions including chronic inflammatory processes, infections, environmental agents, exposure to ionizing radiation, chronic conditions, and certain medications. Symptoms include shortness of breath, coughing, and diminished exercise tolerance. Treatment options are dependent on the type of pulmonary fibrosis; lung transplant and/or medications are optons.
Pulmonary hypertension is an abnormal elevation of the pressure in the pulmonary circulation caused by the constriction of the blood vessels that supply blood to the lungs. Shortness of breath and dizziness are symptoms of pulmonary hypertension. Treatment involves diuretics, blood thinners, calcium channel blockers, and using supplemental oxygen to increase blood oxygen levels.
Smoking is an addiction. More than 430,000 deaths occur each year in the U.S. from smoking related illnesses. Secondhand smoke or "passive smoke" also harm family members, coworkers, and others around smokers. There are a number of techniques available to assist people who want to quit smoking.
Heart failure is caused by many conditions including coronary artery disease, heart attack, cardiomyopathy, and conditions that overwork the heart. Symptoms of heart failure include congested lungs, fluid and water retention, dizziness, fatigue and weakness, and rapid or irregular heartbeats.
Asbestos exposure lung disease is divided into three main types, asbestosis (lung scarring caused by asbestos fibers), disease of the lining of the lung (pleural plaques, scarring, or fluid accumulation), and lung cancer. Mesothelioma is cancer of the lining of the lung caused by asbestos exposure. Cancers of the larynx, throat, kidney, esophagus, and gallbladder have been linked to asbestos exposure. Treatment is dependant upon the type of condition related to asbestos exposure.
Hypersensitivity Pneumonitis is an inflammation of the lung caused by small airborne particles such as bacteria, mold, fungi, or inorganic matter. There are two types of hypersensitivity pneumonitis, acute and chronic. Symptoms include fever, chills, cough, shortness of breath, body aches. Examples of hypersensitivity pneumonitis include bagassosis, mushroom worker's disease, sauna taker's disease, pigeon breeder's disease, and farmer's lung disease. Most commonly, it results from exposure to pet birds.
What is hypersensitivity pneumonitis and what
causes it?
Hypersensitivity pneumonitis is an inflammation of the
lung (usually of the very small airways) caused by the body's immune
reaction to small air-borne
particles. These particles can be bacteria, mold, fungi, or even
inorganic matter.
What is acute hypersensitivity pneumonitis?
Acute hypersensitivity pneumonitis tends to occur 4-12 hours after exposure (usually heavy exposure) to the particles.
What are the symptoms of acute hypersensitivity pneumonitis?
Symptoms of acute hypersensitivity pneumonitis include:
fever,
chills,
coughing,
shortness of breath,
body aches, etc.
Chest x-rays may show diffuse small nodules in the lungs. Typically, the symptoms will subside hours to days after exposure (provided there are no repeated exposures). The Chest x-ray abnormalities w...