If you use ASP.NET AJAX and you or any of the people who use your site use Google Chrome, you might find that it causes trouble (this is actually a problem with ASP.NET AJAX, not Chrome – it also doesn’t like the latest version of Safari, which is also based on WebKit, the engine that Chrome uses for rendering HTML).Anyway, you might want to look at this blog entry - they have come up with a nice solution to the problem. I’ve tried it and it works really well.