Johns Hopkins Medicine News

Arnall Patz, director emeritus of the Wilmer Eye Institute at Johns Hopkins; a pivotal figure in the history of ophthalmology; and the recipient of both a Presidential Medal of Freedom and an Albert Lasker Award, often called the “American Nobel,” for his groundbreaking research into the causes and prevention of blindness, died on March 10.

Johns Hopkins University’s newly formed Brain Science Institute’s NeuroTranslational Program has entered into a licensing agreement with pharmaceutical company Eisai Inc. to discover and develop small molecule glutamate carboxypeptidase II (GCPII) inhibitors.

African-American, Hispanic, and economically disadvantaged patients with brain tumors are significantly less likely to be referred to high-volume hospitals that specialize in neurosurgery than other patients of similar age, the same gender, and with similar comorbidities, according to new research by Johns Hopkins doctors. The finding, published in the March Archives of Surgery, suggests a scenario in direct contrast to recommendations from federal health care agencies encouraging better access and quality of health care for people of all races.

People whose “bad” cholesterol and risk of future heart disease stay too high despite cholesterol-lowering statin therapy can safely lower it by adding a drug that mimics the action of thyroid hormone. In a report published in the Mar. 11, issue of the New England Journal of Medicine, Johns Hopkins and Swedish researchers say an experimental drug called eprotirome lowered cholesterol up to 32 percent in those already on statins, an effect equal to that expected from doubling the statin drug doses, without harmful side effects.

In a landmark study of more than 80,000 live kidney donors from across the United States, Johns Hopkins researchers have found the procedure carries very little medical risk and that, in the long term, people who donate one of their kidneys are likely to live just as long as those who have two healthy ones.

The Johns Hopkins University School of Medicine has been awarded a $9.7 million federal grant to study ways to improve cardiovascular outcomes among African-American patients and to understand and reduce racial and ethnic disparities in blood pressure management in Baltimore.

The Johns Hopkins Hospital has again received the 2010 American Alliance of Healthcare Providers’ (AAHCP) American Hospital of Choice Award. Johns Hopkins has been selected for this award seven times since the award’s inception in 2002.

In reports of two new studies, researchers led by Johns Hopkins say they have identified the mechanisms rooted in two anatomical brain abnormalities that may explain the onset of schizophrenia and the reason symptoms don’t develop until young adulthood. Both types of anatomical glitches are influenced by a gene known as DISC1, whose mutant form was first identified in a Scottish family with a strong history of schizophrenia and related mental disorders. The findings could lead to new ways to treat, prevent or modify the disorder or its symptoms.