National Institute of Mental Health, Medications
FDA, Antidepressant Use in Children, Adolescents, and Adults
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Antidepressant Side Effects
A new study says over half of all people treated with antidepressants stop taking them because of side effects. See more WebMD Videos »
Cymbalta is approved for the treatment of depression.
Important Safety Information
Cymbalta® (duloxetine HCl) is approved for the treatment of depression and generalized anxiety disorder, and for the management of diabetic peripheral neuropathic pain and fibromyalgia.
Patients on antidepressants and their families or caregivers should watch for new or worsening depression symptoms, unusual changes in behavior, thoughts of suicide, anxiety, agitation, panic attacks, difficulty sleeping, irritability, hostility, aggressiveness, impulsivity, restlessness, or extreme hyperactivity. Call your healthcare provider right away if you have thoughts of suicide or if any of these symptoms are severe or occur suddenly. Be especially observant within the first few months of antidepressant treatment or whenever there is a change in dose.
You should not take Cymbalta if:
Before starting Cymbalta, tell your healthcare provider:
While taking Cymbalta, tell your healthcare provider:
If you have any questions, talk to your healthcare provider before taking Cymbalta.
The most common side effect of Cymbalta was nausea. For most people who had it, the nausea was mild to moderate. Other common side effects included dry mouth, sleepiness, constipation, decreased appetite, and, increased sweating. This is not a complete list of side effects.
Depression is a potentially life-threatening mood disorder that affects up to 12% of the population, or approximately 17.6 million Americans each year.
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