Cell Cycle and Cytokinesis
Cell Cycle Regulation and the Control of Cell Proliferation (Cell Growth +
Cell Division)
- Cell Cycle-Dependent
Genes - Links to gene database information on E2F and RB pathway members,
cyclins and cyclin-dependent kinases, cell cycle-dependent phosphatases,
inhibitors of cyclin-dependent kinases, p53 pathway , mdm2, p14ARF and
transcription factors regulating G0/G1 transition. (O.V. Kel-Margoulis;
part of the Transcription
Regulatory Regions Database)
- The
Eukaryotic Cell Cycle and Cancer - Introduction to the eukaryotic cell
cycle as it relates to the genetics of cancer. (Phillip McClean, North Dakota
State University) (Just above Beginner's Level)
- ICRF
FACS Laboratory Cell Cycle Analysis - Methods for cell cycle analysis
using flow cytometry. (FACS Laboratory, Imperial Cancer Research Fund, UK)
- The Interactive
Fly: Evolutionarily Conserved Pathways (Society for Developmental Biology).
Includes sections on:
- Kimball's
Biology Pages: The Cell Cycle - Basic information on the cell cycle
(G1 = Gap 1 phase, growth and preparation of the chromosomes for replication;
S = synthesis of DNA and centrioles; G2 = Gap 2, preparation for M = mitosis).
(Beginner's Level)
- Kyoto Encyclopedia of Genes and Genomes
(KEGG) - Includes graphical and hypertext-based information on biochemical
pathways, including metabolic and regulatory pathways (for instance, cell
cycle and growth factor signaling).
- The
Ubiquitin System for Protein Modification and Degradation - A broad
range of information on the ubiquitin/proteasome pathway, the proteolytic
system that helps control cell cycle progression by the regulated degradation
of cell cycle proteins like the cyclins.
- Wikipedia - Free online encyclopedia
with basic overviews. (Beginner's Level)
- Yeast Cell Cycle Analysis
Project - The goal of this project is to identify all genes whose mRNA
levels are regulated by the cell cycle.
See also the Apoptosis, Cell
Senescence and Signal Transduction
pages.
Mitosis, Meiosis and the Mechanics of Cell Division
- The Biology Project - Tutorials,
lessons and quizzes on basic biology. (University of Arizona) (Beginner's
Level)
- The
Cytokinetic Mafia - Web site devoted to cytokinesis.
- MIT Biology Hypertextbook:
Mitosis - Tutorial on mitosis. (Beginner's Level)
- Mitosis
World - Resources for people studying mitosis.
- Plant Cytokinesis -
Information on and mages of cytokinesis in plants. (Chun-Ming Liu, Plant
Research International, Wageningen, Wageningen, The Netherlands)
- Plant Mitosis - Information
on and mages of mitosis in plants. (Chun-Ming Liu, Plant Research International,
Wageningen, The Netherlands)
- On-Line
Biology Book - Comprehensive introduction to biology at the "college
freshman" level by M.J. Farabee. (Beginner's
Level)
- A
Web Atlas of Cellular Structures: Stages of Mitosis - Confocal microscope
images of cells in different stages of mitosis with brief text descriptions.
(Beckman Institute for Advanced Science and Technology at the University
of Illinois, Urbana-Champaign) (Just above Beginner's
Level)
- Wikipedia - Free online encyclopedia
with basic overviews. (Beginner's Level)
See also the Cytoskeleton, Cell Motility and
Motors page.
Cancer Resources
A major component of cancer progression is the loss of normal controls on
cell proliferation (disruption of normal cell cycle regulation and cell
signaling), in addition to other changes involving angiogenesis,
cell adhesion, invasion
and metastasis. There exist many resources and gateways to cancer
information on the Web, including:
- American Cancer Society
- CancerGuide: Cancer Basics -
Basic information on cancer and links to more specialized resources dealing
with individual types of cancer. (Steve Dunn) (Beginner's
Level)
- Cancer Helper - Basic information
on cancer. (Beginner's Level)
- Cancer Research UK - Science
and Research - "On this page you will find links to other CR-UK
Science and Research web pages including our Scientific Reports and application
procedures."
- Categories
of Cancer/Cancer Classification
- Kimball's
Biology Pages - A comprehensive online biology textbook. (Beginner's
Level)
- Cancer
- Basic information on cancer.
- Oncogenes
- Tutorial on oncogenes, the cancer-promoting form of positive growth
control genes.
- Tumor
Suppressor Genes - Tutorial on tumor suppressor genes (anti-oncogenes).
- National Cancer Institute (NCI)
- Cancer.gov - NCI's comprehensive
cancer information resource.
- Cancer Facts - A "collection
of fact sheets that address a variety of cancer topics."
- Dictionary of Cancer Terms
- Understanding
Cancer Series - Slide-based overviews of cancer, the immune system,
cancer genomics,
angiogenesis
, estrogen receptor/SERMs, genetic variation (SNPs), gene testing, cancer genome
project and nanodevices.
- Nova Online: Cancer
Warrier: How Cancer Grows (Beginner's Level)
- The Medical Biochemistry
Page - An excellent biochemistry tutorial with information on a broad
range of biochemical pathways. (Michael W. King, Terre Haute Center for Medical
Education, Indiana University School of Medicine)
- OncoLink - Large cancer resource
site. (Abramson Cancer Center of the University of Pennsylvania)
- Open Directory:
Health: Conditions and Diseases: Cancer
- The p53 Home Page - A range of resources
related to the p53 tumor suppressor and cancer.
- Wikipedia - Free online encyclopedia
with basic overviews. (Beginner's Level)
- Yahoo:
Health: Diseases and Conditions: Cancer
See also the Tumor Cell Invasion and Metastasis
section of the Cytoskeleton, Cell Motility and
Motors page and the Angiogenesis, Cell
Adhesion and Extracellular Matrix and Signal
Transduction pages.
Discussion Group
See also the Discussion
Groups section of the General
Biochemistry and Cell Biology page.
Labs Studying