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The risk of serious complications from induced abortion: do personal characteristics make a difference?

Am J Obstet Gynecol. 1985 Sep 1;153(1):14-20. doi: 10.1016/0002-9378(85)90582-4.

Abstract

We examined the age, gestational age, parity, race, and number of previous spontaneous and induced abortions of 82,030 women who obtained abortions at less than or equal to 24 weeks' gestation. Among these women, 342 (0.4%) had serious complications, including 130 (0.2%) with fever greater than or equal to 38 degrees C for 3 or more days, 172 (0.2%) who required transfusions, 67 (0.1%) who required unintended surgery, and three who died. Factors significantly (p less than 0.05) associated with serious complications varied by period of gestation, including previous induced abortions (adjusted relative risk = 1.57, 95% confidence interval = 1.03 to 2.40) for procedures done at less than or equal to 12 weeks' gestation, advancing age (relative risk for a 5-year increment = 1.12, 95% confidence interval = 1.01 to 1.24), and advancing gestational age (relative risk for a 2-week increment = 1.50, 95% confidence interval = 1.43 to 1.57) for procedures done at greater than 12 weeks, and greater than or equal to 1 previous delivery (relative risk = 1.34, 95% confidence interval = 1.03 to 1.75) for all gestational ages. Although Hispanic women had higher rates of complications compared with white women, data were not available to control for socioeconomic status in comparing race groups. There was no significant association between previous spontaneous abortions and serious complications. Risk patterns were similar, but not identical, when fever, operation, and transfusion were considered separately.

PIP: The authors examined the age, gestational age, parity, race, and number of previous spontaneous and induced abortions of 82,030 women who obtained abortions at less than 24 weeks' gestation. Among these women, 342 (0.4%) had serious complications, including 130 (0.2%) with fever of over 38 degrees Centigrade for 3 or more days, 172 (0.2%) who required transfusions, 67 (0.1%) who requied unintended surgery, and 3 who died. Factors significantly (p 0.05) associated with serious complications varied by period of gestation, including previous induced abortions (adjusted relative risk = 1.57, 95% confidence interval = 1.03 to 2.40) for procedures done at less than 12 weeks' gestation, advancing age (relative risk for a 5-year increment = 1.12, 95% confidence interval = 1.01 to 1.24), and advancing gestational age (relative risk for a 2-week increment = 1.50, 95% confidence interval = 1.43 to 1.57) for procedures done at more than 12 weeks, and moe than 1 previous delivery (relative risk = 1.34, 95% confidence interval = 1.03 to 1.75) for all gestational ages. Although Hispanic women had higher rates of complications compared with white women, data were not available to control for socioeconoimic status in comparing race groups. There was no significant association between previous spontaneous abortions and serious complications. Risk patterns were similar but not identical when fever, operation, and transfusion were considered separately.

MeSH terms

  • Abortion, Induced / adverse effects*
  • Abortion, Spontaneous / epidemiology
  • Adult
  • Blood Transfusion
  • Cervix Uteri / injuries
  • Cervix Uteri / surgery
  • Ethnicity
  • Female
  • Fever / etiology
  • Gestational Age
  • Humans
  • Maternal Age
  • Parity
  • Pregnancy
  • Regression Analysis
  • Risk
  • Socioeconomic Factors
  • Uterine Hemorrhage / etiology
  • Uterine Hemorrhage / therapy
  • Uterine Perforation / etiology
  • Uterine Perforation / surgery