Background There have been no studies of the patterns of post-marketing withdrawals of
medicinal products to which adverse reactions have been attributed. We identified medicinal
products that were withdrawn because of adverse drug reactions, examined the evidence to
support such withdrawals, and explored the pattern of withdrawals across countries.
Methods We searched PubMed, Google Scholar, the WHO's database of drugs, the websites
of drug regulatory authorities, and textbooks. We included medicinal products withdrawn …

Background We identified anti-obesity medications withdrawn since 1950 because of
adverse drug reactions after regulatory approval, and examined the evidence used to
support such withdrawals, investigated the mechanisms of the adverse reactions, and
explored the trends over time. Methods We conducted searches in PubMed, the World
Health Organization database of drugs, the websites of drug regulatory authorities, and
selected full texts, and we hand searched references in retrieved documents. We included …