Effects of coenzyme Q10 in early Parkinson disease: evidence of slowing of the functional decline
CW Shults, D Oakes, K Kieburtz, MF Beal… - Archives of …, 2002 - jamanetwork.com
Background Parkinson disease (PD) is a degenerative neurological disorder for which no
treatment has been shown to slow the progression. Objective To determine whether a range
of dosages of coenzyme Q 10 is safe and well tolerated and could slow the functional
decline in PD. Design Multicenter, randomized, parallel-group, placebo-controlled, double-
blind, dosage-ranging trial. Setting Academic movement disorders clinics. Patients Eighty
subjects with early PD who did not require treatment for their disability. Interventions …
treatment has been shown to slow the progression. Objective To determine whether a range
of dosages of coenzyme Q 10 is safe and well tolerated and could slow the functional
decline in PD. Design Multicenter, randomized, parallel-group, placebo-controlled, double-
blind, dosage-ranging trial. Setting Academic movement disorders clinics. Patients Eighty
subjects with early PD who did not require treatment for their disability. Interventions …