A volumetric magnetic resonance imaging study of monozygotic twins discordant for bipolar disorder

JT Noga, K Vladar, EF Torrey - Psychiatry Research: Neuroimaging, 2001 - Elsevier
Six monozygotic (MZ) twin pairs discordant for bipolar disorder were compared with normal
MZ twins with magnetic resonance imaging (MRI) on volumes of basal ganglia (BG),
amygdala-hippocampus (AH), and cerebral hemisphere. Caudate nuclei were larger in both
affected and unaffected bipolar twins than in normal MZ twins. The right hippocampus was
smaller in the sick vs. well bipolar twins. The hippocampus was also less asymmetric in the
affected bipolar twins than in the well cotwins and the normal MZ twins. These anatomical …