First steps towards the genetic manipulation of Mycoplasma agalactiae and Mycoplasma
bovis using modified Tn4001 transposons … Acceptable use policy … First steps towards
the genetic manipulation of Mycoplasma agalactiae and Mycoplasma bovis using modified
Tn4001 transposons …

Mycoplasma agalactiae and M. bovis rank amongst the most serious pathogenic
mycoplasmas infecting small ruminants and cattle, respectively. Despite considerable
advances made in Mycoplasma molecular genetics in the past decade, there is still a
complete lack of genetic tools to assess the pathogenic mechanisms of these two species.
Studies were undertaken to develop a genetic system for the analysis of potential virulence
factors of these pathogens. Transposon Tn4001mod was successfully introduced into …