[PDF][PDF] A Randomized

K Awadzi, NO Opoku, SK Attah… - … , Ivermectin-Controlled …, 2014 - academia.edu
Background: Control of onchocerciasis as a public health problem in Africa relies on annual
mass ivermectin distribution. New tools are needed to achieve elimination of infection. This
study determined in a small number of Onchocerca volvulus infected individuals whether
moxidectin, a veterinary anthelminthic, is safe enough to administer it in a future large study
to further characterize moxidectin's safety and efficacy. Effects on the parasite were also
assessed. Methodology/Principal Findings: Men and women from a forest area in South …

A Randomized, Single-Ascending-Dose, Ivermectin-Controlled, Double-Blind Study of Moxidectin in Onchocerca volvulus Infection

K Awadzi, NO Opoku, SK Attah… - PLoS neglected …, 2014 - journals.plos.org
Background Control of onchocerciasis as a public health problem in Africa relies on annual
mass ivermectin distribution. New tools are needed to achieve elimination of infection. This
study determined in a small number of Onchocerca volvulus infected individuals whether
moxidectin, a veterinary anthelminthic, is safe enough to administer it in a future large study
to further characterize moxidectin's safety and efficacy. Effects on the parasite were also
assessed. Methodology/Principal Findings Men and women from a forest area in South …
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