Damage to the central nervous system (CNS) elicits the activation of both astrocytes and
microglia. This review is focused on the principal features that characterize the activation of …

The role of glial cells is to support and sustain proper neuronal function and microglia are no
exception to this. This viewpoint article emphasizes the fundamental interdependence of …

The present review summarizes recently acquired data in vivo, which support a role of CNS
microglia as a source of defense cells in the CNS capable of carrying out certain immune …

The role of microglial cells in the pathogenesis of Alzheimer's disease (AD)
neurodegeneration is unknown. Although several works suggest that chronic …

We have studied microglial morphology in the human cerebral cortex of two nondemented
subjects using high‐resolution LN‐3 immunohistochemistry. Several abnormalities in …

Microglial research has advanced considerably in recent decades yet has been constrained
by a rolling series of dichotomies such as" resting versus activated" and" M1 versus M2." …

The past 20 years have seen a gain in knowledge on microglia biology and microglia
functions in disease that exceeds the expectations formulated when the microglia “immune …

This paper summarizes pathological changes that affect microglial cells in the human brain
during aging and in aging-related neurodegenerative diseases, primarily Alzheimer's …

Microglia are seen as the sentries in the CNS who provide a first line of defense whenever
there is injury or disease. Microglia and related perivascular macrophages perform various …

We have studied temporal mRNA expression patterns for interleukin-1β (IL-1β), tumor
necrosis factor-α (TNF-α), interleukin-6 (IL-6), macrophage colony stimulating factor (M …