The receptors and cells for mammalian taste

J Chandrashekar, MA Hoon, NJP Ryba, CS Zuker - Nature, 2006 - nature.com
The emerging picture of taste coding at the periphery is one of elegant simplicity. Contrary to
what was generally believed, it is now clear that distinct cell types expressing unique …

[HTML][HTML] Common sense about taste: from mammals to insects

DA Yarmolinsky, CS Zuker, NJP Ryba - Cell, 2009 - cell.com
The sense of taste is a specialized chemosensory system dedicated to the evaluation of food
and drink. Despite the fact that vertebrates and insects have independently evolved distinct …

[HTML][HTML] Coding of sweet, bitter, and umami tastes: different receptor cells sharing similar signaling pathways

Y Zhang, MA Hoon, J Chandrashekar, KL Mueller… - Cell, 2003 - cell.com
Mammals can taste a wide repertoire of chemosensory stimuli. Two unrelated families of
receptors (T1Rs and T2Rs) mediate responses to sweet, amino acids, and bitter …

[PDF][PDF] A new multigene family of putative pheromone receptors

NJP Ryba, R Tirindelli - Neuron, 1997 - cell.com
The vomeronasal organ (VNO) mediates detection of pheromones related to social and
reproductive behavior in most terrestrial vertebrates. We have identified a new multigene …

[HTML][HTML] Mammalian sweet taste receptors

G Nelson, MA Hoon, J Chandrashekar, Y Zhang… - Cell, 2001 - cell.com
The sense of taste provides animals with valuable information about the quality and
nutritional value of food. Previously, we identified a large family of mammalian taste …

[HTML][HTML] T2Rs function as bitter taste receptors

J Chandrashekar, KL Mueller, MA Hoon, E Adler… - Cell, 2000 - cell.com
Bitter taste perception provides animals with critical protection against ingestion of
poisonous compounds. In the accompanying paper, we report the characterization of a large …

[HTML][HTML] The receptors for mammalian sweet and umami taste

GQ Zhao, Y Zhang, MA Hoon, J Chandrashekar… - Cell, 2003 - cell.com
Sweet and umami (the taste of monosodium glutamate) are the main attractive taste
modalities in humans. T1Rs are candidate mammalian taste receptors that combine to …

The cells and logic for mammalian sour taste detection

AL Huang, X Chen, MA Hoon, J Chandrashekar… - Nature, 2006 - nature.com
Mammals taste many compounds yet use a sensory palette consisting of only five basic taste
modalities: sweet, bitter, sour, salty and umami (the taste of monosodium glutamate) …

[HTML][HTML] A novel family of mammalian taste receptors

E Adler, MA Hoon, KL Mueller, J Chandrashekar… - Cell, 2000 - cell.com
In mammals, taste perception is a major mode of sensory input. We have identified a novel
family of 40–80 human and rodent G protein–coupled receptors expressed in subsets of …

The cells and peripheral representation of sodium taste in mice

J Chandrashekar, C Kuhn, Y Oka, DA Yarmolinsky… - Nature, 2010 - nature.com
Salt taste in mammals can trigger two divergent behavioural responses. In general,
concentrated saline solutions elicit robust behavioural aversion, whereas low concentrations …