The development of an efficient catalytic activation (cleavage) system for C− H and C− C
bonds is an important challenge in organic synthesis, because these bonds comprise a …

Microneedles were first conceptualized for drug delivery many decades ago, but only
became the subject of significant research starting in the mid-1990's when microfabrication …

During recent decades vast and continuously increasing numbers of biomedical implants
have been introduced for continuous use in the human body. Since the early cemented hip …

We generated, on titanium surfaces, self-assembled layers of vertically oriented TiO2
nanotubes with defined diameters between 15 and 100 nm and show that adhesion …

Importance There is limited information about the clinical course and viral load in
asymptomatic patients infected with severe acute respiratory syndrome coronavirus 2 (SARS …

In the G-protein-coupled receptor (GPCR) rhodopsin, the inactivating ligand 11-cis-retinal is
bound in the seven-transmembrane helix (TM) bundle and is cis/trans isomerized by light to …

OBJECTIVE:: To investigate the relationship between serum concentrations of the cytokines
C-reactive protein (CRP), tumor necrosis factor (TNF)-α, and interleukin (IL)-6, and obesity …

Survival of naive T cells is dependent upon IL-7, which is present in vivo in limiting amounts
with the result that naive T cells must compete for IL-7-mediated survival signals. It would …

Opsin, the ligand-free form of the G-protein-coupled receptor rhodopsin, at low pH adopts a
conformationally distinct, active G-protein-binding state known as Ops*. A synthetic peptide …

The antibacterial effect of silver nanoparticles has resulted in their extensive application in
health, electronic, and home products. Thus, the exposed population continues to increase …